BREAST STUDIES
Breast
Novartis CRAD0012301
Phase III, Double-Blind, Placebo-Controlled Study of Dail Everolimus in Combination
with Trastuzumab and Vinorelbine in Pretreated Women with HER2/newu Over-Expressing
Locally Advanced or Metastatic Breast Cancer
Breast TNBC
Roche Genentech OAM4861g
Phase III Randomized, Double-Blind Study Cmoparing METMAb + Bvacizub + Paclitaxel
and MetMab + Placebo + Paclitaxel Relative to Placebo + Bevacizumab + Placlitaxel,
in the 1st and 2nd Line Treatment of Metastatic or Locally Recurrent, Triple-Negative
Breast Cancer
Breast Cancer
Amgen D-Care
A Randomized, Double-Blind, Placebo-Controlled, Multi-Center Phase III Study of
Denosumab as Adjuvant or Neoadjuvant Treatment for Women with Early-Stage Breast
Cancer at High Risk of Recurrence (D-Care)
Breast Cancer
Roche-Genetech TDM4997g
A Phase III Randomized, Multcenter, Two-Arm Open-Label Trial To Evaluate the Efficacy
of T-DM1 cmopared with treatment of physician's choice in patients with HER2-Positive
Metastatic Breast Cancer who have received at least two prior regimens of HER2-Directed
Therapy
Breast Cancer
Roche BO22589/TDM4788g
Phase III, Study to evaluate the efficacy and the safety of T-DM1 Combined with
pertuzumab vs T-DM1 (Blinded for Pertuzumab), vs Trastuzumab plus Taxane, as 1st
Line Treatment in HEr-2 Positive Metastatic Breast Cancer.
Breast Cancer
Novartis CZOL446EUS147 Z-Act 1
Phase IV, Open-label, Study of the anti-cancer effects of Zoledronic Acid in combination
with CHemotherapy +/- Avastin or Hormonal Therapy using Circulating Tumor Cell Measurements
(CTC'S) in the 1st Line and 2nd Line Treatment of patients with HER2-negative MBC
without Bone Metastases
Breast Cancer
Incyte INCB7839-204
A Phase I/II Study to assess the safety and therapeutic effect of INCB007839 in
combination with Transtuzumab and vinorelbine metastatic HER2 + MBC
Breast Cancer
CDX-011
Phase III, Open Label, Study of CDX-011 vs Investigator Choice Chemotherapy in the
3rd-8th line Treatment of patients with BPNMB-expressing MBC
Breast Cancer
Novartis CZOL446E2352 Optimize 2
Phase II, Double-Blind, Study of the continued efficacy and safety of Zometa (every
4 weeks vs. every 12 weeks) in patients with documented bone metastases from Breast
Cancer
Breast Cancer
Bayer BAY43-9006/12444
Phase III Double Blind Trial of Capecitabine plus Sorafenib vs. Capecitabine plus
placebo in the t1st and 2nd Line Treatment of Locally advanced or Stage IV HER 2
Negative Breast Cancer
COLORECTAL STUDIES
Metastatic Colorectal Cancer
Genentech MAVVERICC ML 25710
A Randomized Phase II Study of Bevacizumab/mFOLFOX vs Bevacizumab/Folfiri with Biomarker
Stratification in Patients with Previously Untreated Metastatic Colorectal Cancer
Metastatic Colorectal Cancer
Daiichi ARQ 197
Phase 1/2 Trial of Placebo-Controlled, ARQ 197 in Combination with Irinotecan and
Cetuximab in the Treatment of Subjects wtih Metastatic Colorectal Cancer with Wild-Type
DRAS who have received Front-Line Systemic Therapy
LUNG CANCER STUDIES
Lung
BioNumerik DMS32212R
Randomized, Multicenter, Double-Blind, Phase III Trial of Tavocept vs. Plaebo in
Patients with Newly Diagnosed or Relapse Advanced Primary Adenocarcinoma of the
Lung Treated with Docetaxel or Paclitaxel + Cisplatin
Lung
MEDIMUNE
Phase 1b/2 Randomized Study of MEDI-575 in combination with Carboplatin plus Paclitaxol
vs. Carboplatin Plus alone in 1st Line Treatment of Advanced NSCLC
MYELOMA, LYMPHOMA, ITP
Multiple Myeloma
Keryx Perifosine 339
Phase III Randomized Study to assess the efficacy and Safety of Perifosine added
to the Combinatino of Bortezomib and Dexamethasone in Multiple Myeloma Patients
previously Treated with Bortezomib
Multiple Myeloma
Celgene Connect MM
The multiple Myeloma Disease Registry
ITP
Immunomedics IM-T-ha20-07
A phase I/II Study of Immunotherapy with Humanized Anti-CD20 Antibody, Immu-106
(hA20) in Adult Patients with Chronic ITP
B-Cell Non Hodgkins Lymphoma
Cell Therapeutics PIX306
Randomized, Multicenter Study Comparing Pixantrone + Rituximab with Gemcitabine
+ Rituximab in patients with Aggressive B-Cell NHL who have relpased after therapy
with CHOP-R or an Equivalent Regimen and are inelligible for Stem Cell Transplant.
Follicular Lymphoma
10 GSK Home OMB113676
Phase III Randomized, Open Label Study of Single Agent Ofatumamab vs. Single Agent
Rituximab in Follicular Lymphoma relapsed after Rituximab-Containing Therapy.
PANCREATIC
Pancreatic
Abraxis CA046
Phase III Randomized Study of Weekly ABI-007 Plus Gemcitabine vs. Gemcitabine Alnoe
in 1st Line Treatment of Patients with Metastatic Pancreatic Adenocarcinoma.
Pancreatic
Clovis CO-101-001
Phase II Open-Label, Multicenter Study Comparing CO-1.01 with Gemcitabine as 1st
Line Treatment in Metastatic Pancreatic Adenocarcinoma
Pancreatic
Clovis CO-101-001
Phase II Open-Label, Multicenter Study Comparing CO-1.01 with Gemcitabine as 1st
Line Treatment in Metastatic Pancreatic Adenocarcinoma
Pancreatic
Peregrine PPHM 1002
Phase II Open Label, Trail of Gemcitabine with or without Bavituximab in 1st Line
treatment of Metastatic Pancreatic Adenocarcinoma
Pancreatic
Theradex/KangLaiTE-USA
Phase 2b Randomized, Dose Escalation study of the Safety and exploratory Efficacy
of Kanglaite Injection plus Gemcitabine (G+K) vs Gemcitabnie in the 1st line treatment
of patients with Advanced Pancreatic Cancer
POLYCYTHEMIA VERA
Polycythemia Vera
Incyte INCB 18424-356
A Randomized Study of the JAK Inhibitor INCB018424 Tablets compared to Best Available
Therapy in subjects wtih Polycythemia Vera Who are Resistant to Hydroxyurea
PROSTATE
Prostate
BMS CA184095
A Randomized, Double Blinded, Phase III Trial to Compare the efficacy of Ipilimumbab
vs. Placebo in Asymptomatic or Minimally Symptomatic Patients with Mestastatic Chemo-Naive
CRPC
OVARIAN
Ovarian
Morphotek MORab-003-004PS
Phase III Randomized, Double-Blind, Placebo-Controlled to assess the Efficacy and
Safety of Weekly Farletuzumab (MORAb-003) in Combination with Carboplatin and Taxane
in subjects with Platinum-Sensitive Ovarian Cancer in First Relapse.
Ovarian
Morab0003-003PR
Phase III Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and
Safety of MORAb-003 (Farletuzumab) in combination with Paclitaxel in subjects wtih
Platinum-resistant or Refractory Relapsed Ovarian Cancer
SOLID TUMORS
Solid Tumors
Investigator Initiated
Phase I/II Study of Disulfiram, Capecitabine and Copper Gluconaet for the treatment
of Refractory Solid Tumors.